Medical Publications

Browse the medical publications below to learn more about saline nasal irrigation, and how it can help relieve sinusitis and rhinosinusitis.

Management of Allergic Rhinitis Patients With Nasal Steroids and NeilMed® Sinus Rinse™ System With Isotonic Saline. 

Dr. Shaun A. Nguyen & Dr. Rodney J. Schlosser, Medical University of South Carolina

The purpose of this study is to compare quality of life outcomes in patients who continue medical treatment plus the use of the NeilMed Sinus Rinse low-pressure pump with saline.

Role of saline nasal irrigation in the treatment of chronic rhinosinusitis

Author: Dr. Brindusa Petrutescu, MD, Allergology and Clinical Immunology, Bucharest, Romania

Use of saline nasal cleansing as non-drug treatment in many diseases of the nose and sinuses is not a novel concept. In yoga tradition and homeopathic medicine nasal lavage is a ritual, along with daily teeth-brushing.


Validation of the Sino-Nasal Outcome Test 20 (SNOT-20) domains in nonsurgical patients

Melissa A. Pynnonen, M.D., H. Myra Kim, Sc.D. and Jeffrey E. Terrell, M.D.

Subscales identified differences in the impact of two medical interventions on chronic sinonasal symptoms. Reporting subscale scores might improve the precision of the SNOT-20 instrument, allowing discrimination between various treatments and their differential impact on sinonasal quality of life.

FAMILY PRACTICE JOURNAL - Saline irrigation spells relief for sinusitis sufferers

Encourage patients with chronic rhinosinusitis to try this simple approach, January 2009 (Vol. 58, No. 1)

Mari Egan, MD, MHPE; John Hickner, MD, MS. Department of Family Medicine, The University of Chicago

Otolaryngologists recommend saline irrigation after sinus surgery to clear secretions, debris, and crusts; reduce the risk of postoperative mucosal adhesions; and expedite mucosal healing. Saline irrigation is also gaining popularity as an alternative approach to chronic sinusitis symptom relief, and several randomized controlled trials (RCTs) have demonstrated both objective and subjective efficacy of this treatment for sinonasal disease.

AAOHNS - Effects of endoscopic sinus surgery and delivery device on cadaver sinus irrigation

Otolaryngology-Head and Neck Surgery (2008) 139, 137-142.ORIGINAL RESEARCH-SINONASAL DISORDERS

Richard J. Harvey, MD, John C. Goddard, MD, Sarah K. Wise, MD, and Rodney J. Schlosser, MD, Charleston, SC; and Atlanta, GA

ESS greatly enhances the delivery of nasal solutions, regardless of delivery device. Pressurized spray solutions in un-operated sinuses provide little more than nasal cavity distribution. Use of squeeze bottle/neti pot post-ESS offers a greatly enhanced ability to deliver solutions to the paranasal sinuses.

Archives of Otolaryngology-Head & Neck Surgery-Nov 2007

Nasal Saline for Chronic Sinonasal Symptoms - A Randomized Controlled Trial

Melissa A. Pynnonen, MD; Shraddha S. Mukerji, MD; H. Myra Kim, ScD; Meredith E. Adams, MD; Jeffrey E. Terrell, MD

Nasal irrigations performed with large volume and delivered with low positive pressure (NeilMed Sinus Rinse) are more effective than saline sprays for treatment of chronic nasal and sinus symptoms in a community based population.

Dr. Mehta's Brochure on Saline Irrigation, Allergies and Sinus Disease

I am a practicing physician in the field of pulmonary and critical care medicine. I suffered for several years from chronic sinus disease. After being evaluated by an Allergist and Ear, Nose, and Throat specialist, I had corrective surgeries on my sinuses. Of all the treatments tried for controlling and curing my symptoms of sinus disease, the one I found to work the best was a saline nasal rinse.

Laryngoscope Journal Article-September 2008

Pre- and Postoperative Sinus Penetration of Nasal Irrigation

Alethea Grobler, MBBS; Erik K. Weitzel, MD; Achim Buele, MD; Camille Jardeleza, MD; Yew C. Cheong, MD; John Field, PhD, AStat; Peter-John Wormald, MD, FRACS

Unoperated sinuses or cases with gross sinus ostial obstruction will not be reliably penetrated by sinus irrigant. A 3.95-mm ostial diameter seems to be the minimum size to guarantee penetration in paranasal sinuses to maximize the potential for topical sinus treatment.


Nasal Lavage With Mupirocin for the Treatment of Surgically Recalcitrant Chronic Rhinosinusitis

Brent Uren, FRACS; Alkis Psaltis, MBBS; Peter-John Wormald, MD

Nasal lavage with a mupirocin solution may represent an effective alternative to manage patients with recalcitrant CRS due to SA infection. It is well tolerated and involves reduced treatment related morbidity when compared with standard oral or systemic drug delivery. Further research is needed to better understand the pharmacodynamics of topical drug use in the sinonasal cavities.

Laryngoscope Journal Article - Aug 2002

Radiographic Comparison of Three Methods for Nasal Saline Irrigation

David E. L. Olson, MD; Barry M. Rasgon, MD; Raymond L. Hilsinger, Jr., MD

Three different methods of nasal irrigations were compared; positive pressure (NeilMed Sinus Rinse), negative pressure and the nebulizer method. Study concluded that irrigations performed by positive pressure penetrated into the ethmoid and maxillary sinuses more consistently than other methods of irrigation.

Rhinology - Baby shampoo nasal irrigations

Baby shampoo nasal irrigations for the symptomatic post-functional endoscopic sinus surgery patient

Alexander G. Chiu, M.D., James N. Palmer, M.D., Bradford A. Woodworth, M.D., Laurel Doghramji, R.N., Michael B. Cohen, B.A., Anthony Prince, B.A., and Noam A. Cohen, M.D., Ph.D.

Baby shampoo nasal irrigation has promise as an inexpensive, tolerable adjuvant to conventional medical therapies for symptomatic patients after FESS. Its greatest benefit may be in improving symptoms of thickened nasal discharge and postnasal drainage.

The Lancet - Rhinitis and onset of asthma: a longitudinal population-based study

Rafea Shaaban, Mahmoud Zureik, David Soussan, Catherine Neukirch, Joachim Heinrich, Jordi Sunyer, Matthias Wjst, Isa Cerveri, Isabelle Pin , Jean Bousquet, Deborah Jarvis, Peter G Burney, Françoise Neukirch, Bénédicte Leynaert

A close relation between asthma and allergic rhinitis has been reported by several epidemiological and clinical studies. However, the nature of this relation remains unclear. We used the follow-up data from the European Community Respiratory Health Survey to investigate the onset of asthma in patients with allergic and non-allergic rhinitis during an 8·8-year period.

Irish Medical Treatment - Allergic rhinitis: new insights, new therapies

Dr. Paul Carson | 02 April 2008 | Eye, Ear, Nose & Throat

Dr. Paul Carson on how his investment in fibre optic technology has provided some new perspectives on allergic rhinitis and the importance of managing the condition At the risk of boring you about a topic many dismiss as trivial, may...

General Medical Literature Review on Saline Nasal Irrigation

Nasal irrigations are often mentioned as adjunctive measures in treating many sinonasal conditions. Despite their widespread use, much mystique and uncertainty exist about the indications and therapeutic mechanisms of nasal irrigations. Anecdotal evidence and poorly controlled studies add to the confusion. Recent evidence challenges some of the assumptions underlying the use of nasal irrigations.

Newspaper and other Medical Publications

Newspaper and other media Publications presenting on NeilMed Sinus Rinse line of Products